211 – Functional state of muscle mitochondria reflects exercise-induced changes in insulin sensitivity and cognitive performance in elderly – J. Ukropec, M. Nemec, D. Maderova, V. Tirpakova, P. Krumpolec, L. Slobodova, M. Vajda, M. Schon, J. Cvecka, Z. Sumbalova, M. Sedliak, B. Ukropcova, Slovakia, Austria

212 – Local-tissue hyperinsulinaemia is a greater risk factor for insulin resistance than hyperglycaemia in type 1 diabetes and MODY2 – J.M. Gregory, T.J. Smith, N.N. Abumrad, A.D. Cherrington, USA

213 – AAV-mediated FgF21 overexpression in skeletal muscle expands healthspan and counteracts insulin resistance – V. Sacristan Fraile, C. Jambrina, E. Casana, S. Muñoz, J. Rodo, S. Darriba, M. Garcia, X. Leon, I. Grass, V. Jimenez, F. Bosch, Spain

214 – Insulin and muscle contraction regulate tBC1D1 through phosphorylation and interaction with the cytosolic tail of insulinregulated aminopeptidase – S. Mafakheri, R.R. Flörke, S. Kanngießer, S. Hartwig, T. Schönberger, N. Hamker, S. Lehr, A. Chadt, H. Al-Hasani, Germany

215 – Diabetes modulates microRnAs 29b-3p, 29c-3p, 199a-5p and 532-3p expression in muscle: potential participation in gLut4 repression – J. Esteves, C.Y. Yonamine, F. Gerlinger-Romero, D.C. Pinto-Junior, F.J. Enguita, U.F. Machado, Brazil, Australia, Portugal

216 – Human skeletal muscle mitochondrial dynamics in relation to insulin sensitivity and oxidative capacity – A. Houzelle, J.A. Jörgensen, G. Schaart, S. Daemen, E. Phielix, M.K. Hesselink, P. Schrauwen, J. Hoeks, Netherlands