466 – Dietary methionine restriction protects from type 2 diabetes in NZO mice – T. Castaño-Martinez, W. Jonas, T. Laeger, Germany

467 – Medium-chain triglyceride oil does not induce GIP secretion and induces less body weight and fat mass gain compared with long-chain triglyceride oil – Y. Murata, N. Harada, S. Yamane, K. Iwasaki, Y. Kanemaru, T. Harada, A. Sankoda, E. Ikeguchi, S. Kuwahara, E. Joo, H. Poudyal, N. Inagaki, Japan

468 – High fat diet induces a blunted antihyperglycaemic effect of the neuropeptide 26RFa in mice – G. Prevost, J. Bons, A. Arabo, M. Picot, J. Maucotel, H. Berrahmoune, M. El Mehdi, S. Cherifi, M. Coeffier, J. Leprince, V. Brunel, P. Dechelotte, H. Lefebvre, Y. Anouar, N. Chartrel, France

469 – Murine lipid-induced hepatic insulin resistance is not pathwayselective – D.F. Vatner, L. Goedeke, X. Li, M.C. Petersen, J.C. Rogers, G. Casals, G.W. Cline, V.T. Samuel, G.I. Shulman, USA

470 – CD44 plays a key role in regulating high fat diet induced muscle insulin resistance – A. Hasib, C.K. Hennayake, D.P. Bracy, D.H. Wasserman, L. Kang, UK, USA

471 – Long-term hypercaloric diet consumption exacerbates age-induced metabolic dysfunction: beneficial effects of CSN denervation – J.F. Sacramento, B.F. Melo, C.S. Prego, S.V. Conde, Portugal

472 – GIP-xenin hybrid peptide enhances the metabolic benefits of exenatide in high fat fed and db/db diabetic mice – V.A. Gault, A. Hasib, M. Ng, R.A. Perry, P.R. Flatt, N. Irwin, UK